The men were randomised to Weight Watchers weight loss programme plus placebo versus the same weight loss programme plus testosteroneor placebo. At the 1-year follow up, the weight loss programmes were associated with weight loss of 4.3% compared with 0.6% in the placebo group (P=0.03). The reduction was greatest in the Weight Watchers programme with an average weight loss of 4, sarm for weight loss.4 kg in the Weight Watchers group vs 3, sarm for weight loss.6 kg in the placebo group (P=0, sarm for weight loss.01), sarm for weight loss. The reduction in overall cardiovascular disease mortality was greatest in the weight loss programme with an overall reduction of 5.5% in the weight loss group vs 0.9% in placebo group (P=0.02), and was greatest in the men receiving the higher doses of testosterone.
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